T cell Generation

Abstract #3425, in ASH symposium, Dec. 2015

• Stimulation of PBMCs from healthy donors
• CD4, CD8 T cells are highly sensitive to IL-7, compared to IL-2, IL-15, IL-6 cytokines.

Blood, 2012, 120, 4882

• In lymphopenic patients after HSCT
• IL-7 increases CD4, CD8 T cells, but not Treg cells.