hyFcTM
- hyFc™ is a platform technology to construct a long-acting fusion partner hybridized with IgD(hinge-CH2) and IgG4(CH2-CH3), as a non-cytolytic and non-immunogenic carrier
- hyFc™ increases half-life, minimizes the loss of bioactivity of drug candidates, and prevents cell killing effect by ADCC and CDC reactions.
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hyFc™ is the next generation immunoglobulin-based, half-life extension technology
- More than 10 pipelines using hyFc™ technology that are currently undergoing preclinical and clinical (Ph1 and Ph2) studies
- 3 phase II ongoing clinical trials of the best-in-class candidates (hGH-hyFc, EPO-hyFc, G-CSF-hyFc) by Genexine, Inc., the platform owner
- > 500 subjects in the clinical trials of hyFc™ products have not experienced any serious adverse event
- According to an in silico analysis, hyFc™ sequences did not include any immunogenic epitope
